Biology

Computational design of dynamic receptor-peptide signaling complexes applied to chemotaxis

R. E. Jefferson, A. Oggier, et al.

This innovative research by Robert E. Jefferson, Aurélien Oggier, and their team explores the engineering of protein biosensors that respond to specific biomolecules, enhancing cellular interactions. The study introduces a computational method to design powerful signaling complexes, showcasing stronger chemotactic responses in human T cells for potential therapeutic applications.... show more

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