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Combining p53 mRNA nanotherapy with immune checkpoint blockade reprograms the immune microenvironment for effective cancer therapy

Medicine and Health

Combining p53 mRNA nanotherapy with immune checkpoint blockade reprograms the immune microenvironment for effective cancer therapy

Y. Xiao, J. Chen, et al.

Discover how restoring p53 expression can transform the immunosuppressive tumor microenvironment in hepatocellular carcinoma. This research demonstrates the powerful synergy of p53 mRNA nanomedicine combined with immune checkpoint blockade therapy, leading to enhanced antitumor effects. A team of experts, including Yuling Xiao and Jiang Chen, conducted this groundbreaking study.

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