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Combinatorial protein dimerization enables precise multi-input synthetic computations
BiologyNature Chemical Biology

Combinatorial protein dimerization enables precise multi-input synthetic computations

A. Bertschi, P. Wang, et al.

Explore a groundbreaking framework that transforms mammalian cells into logic gates through combinatorial protein dimerization, conducted by Adrian Bertschi, Pengli Wang, Silvia Galvan, Ana Palma Teixeira, and Martin Fussenegger. This innovative research reveals how OFF-type gene switches can be activated into ON-type systems, paving the way for complex synthetic computation in biology.... show more
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