Olfactory dysfunction (OD) affects a significant portion of COVID-19 patients. This study investigated clinical and imaging findings in post-COVID-19 OD patients (n=110) compared to a control group (n=50). Results showed that OD was not associated with nasal symptoms in a majority of patients. MRI revealed significantly larger olfactory bulb dimensions and volume in patients, indicating edema and swelling. Olfactory cleft edema was also common. The study concludes that sensorineural loss due to viral damage to olfactory epithelium and pathways is the most likely mechanism for COVID-19 related OD.
Publisher
The Laryngoscope
Published On
Oct 26, 2023
Authors
Eslam Hamed, Elsayed Abdou, Hisham Atef Ebada, Mohammed Abdelbadie Salem, Mahitab Mohamed, Rashad Ghoneim, Fatma Sherif, Elsharawy Kamal
Tags
olfactory dysfunction
COVID-19
MRI
olfactory bulb
sensorineural loss
viral damage
nasal symptoms
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