Medicine and HealthNature Cell Biology
Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration
T. Clapes, A. Polyzou, et al.
Discover how haematopoietic stem cells cleverly elude stress! This study reveals the role of transposable elements and the MDA5 receptor in activating an inflammatory response essential for HSCs to break their quiescence. Conducted by Thomas Clapes and a team at the Max Planck Institute and other esteemed institutions, this research uncovers new insights into haematopoietic regeneration following chemotherapy.
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