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Chemical profiling of DNA G-quadruplex-interacting proteins in live cells

Chemistry

Chemical profiling of DNA G-quadruplex-interacting proteins in live cells

X. Zhang, J. Spiegel, et al.

Discover a groundbreaking co-binding-mediated protein profiling (CMPP) strategy developed by a talented team including Xiaoyun Zhang, Jochen Spiegel, Sergio Martínez Cuesta, Santosh Adhikari, and Shankar Balasubramanian. This innovative approach unveils proteins that interact with DNA G-quadruplexes in live cells, potentially leading to new insights in cellular function and disease mechanisms.

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