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CAR-cell therapy in the era of solid tumor treatment: current challenges and emerging therapeutic advances

Medicine and Health

CAR-cell therapy in the era of solid tumor treatment: current challenges and emerging therapeutic advances

K. M. Maalej, M. Merhi, et al.

This review by leading researchers discusses the potential of CAR-T, CAR-NK, and CAR-M cell therapies in combating solid tumors while addressing the significant challenges these therapies face. Discover innovative strategies being explored to enhance effectiveness and the promising advantages of alternative immune cells.

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~3 min • Beginner • English
Abstract
Publisher
Molecular Cancer
Published On
Jul 18, 2023
Authors
Karama Makni Maalej, Maysaloun Merhi, Varghese P Inchakalody, Sarra Mestiri, Majid Alam, Cristina Maccalli, Honar Cherif, Shahab Uddin, Martin Steinhoff, Francesco M Marincola, Said Dermime
DOI
https://doi.org/https://doi.org/10.1186/s12943-023-01723-z
Tags
CAR-T cell therapy
CAR-NK cells
CAR-M cells
solid tumors
tumor microenvironment
immune effector cells
therapeutic combinations

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