Medicine and Health

Body composition, physical capacity, and immuno-metabolic profile in community-acquired pneumonia caused by COVID-19, influenza, and bacteria: a prospective cohort study

C. K. Ryrsø, A. M. Dungu, et al.

This cohort study delves into the metabolic profiles, body composition, and inflammatory responses of patients with community-acquired pneumonia due to SARS-CoV-2, influenza, or bacteria. The findings reveal a notable increase in inflammatory markers among COVID-19 patients, a crucial insight for understanding their unique clinical features. This research was conducted by Camilla Koch Ryrsø, Arnold Matovu Dungu, Maria Hein Hegelund, Andreas Vestergaard Jensen, Adin Sejdic, Daniel Faurholt-Jepsen, Rikke Krogh-Madsen, and Birgitte Lindegaard.

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Abstract

This prospective cohort study investigated differences in metabolic profile, body composition, physical capacity, and inflammation among patients hospitalized with community-acquired pneumonia (CAP) caused by SARS-CoV-2, influenza, or bacteria. While no significant differences were found in metabolic profiles (glucose, HbA1c, adiponectin, lipids), body composition, or physical capacity across the groups, COVID-19 patients exhibited a heightened inflammatory response, characterized by increased levels of IFN-γ, IL-4, IL-5, IL-6, and IL-10 compared to influenza and bacterial CAP patients.

Publisher

International Journal of Obesity

Published On

Jan 05, 2022

Authors

Camilla Koch Ryrsø, Arnold Matovu Dungu, Maria Hein Hegelund, Andreas Vestergaard Jensen, Adin Sejdic, Daniel Faurholt-Jepsen, Rikke Krogh-Madsen, Birgitte Lindegaard

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