Medicine and Health

Automated detection of intracranial aneurysms using skeleton-based 3D patches, semantic segmentation, and auxiliary classification for overcoming data imbalance in brain TOF-MRA

S. Ham, J. Seo, et al.

This groundbreaking study introduces a CNN model that demonstrates impressive accuracy in detecting intracranial aneurysms through 3D TOF-MRA imaging. Conducted by a team of esteemed researchers, this innovative approach not only highlights the model's capabilities but also suggests significant potential for clinical use.

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Abstract

This study proposes a convolutional neural network (CNN) model for accurate and reliable automated detection of intracranial aneurysms using 3D time-of-flight magnetic resonance angiography (TOF-MRA). The model utilizes 3D patches extracted along vessel skeletons, semantic segmentation with a 3D U-Net, and an auxiliary classifier to address data imbalance. The method achieved high accuracy (0.910 internally, 0.883 externally) and demonstrates potential for clinical application.

Publisher

Scientific Reports

Published On

Jul 11, 2023

Authors

Sungwon Ham, Jiyeon Seo, Jihye Yun, Yun Jung Bae, Tackeun Kim, Leonard Sunwoo, Sooyoung Yoo, Seung Chai, Jeong-Whun Kim, Namkug Kim

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