Medicine and Health

Association of pre-pregnancy body mass index and rate of weight gain during pregnancy with maternal indicators of cardiometabolic risk

L. I. Omaña-guzmán, L. Ortiz-hernández, et al.

This study conducted by Luz Isabel Omaña-Guzmán and colleagues explores the intricate relationship between pre-pregnancy BMI and gestational weight gain on maternal cardiometabolic health. Discover how pre-gestational obesity influences lipid profiles, glucose levels, and blood pressure during pregnancy in a cohort of 720 women in Mexico City.

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Abstract

This prospective cohort study in Mexico City investigated the association between pre-pregnancy BMI (pBMI) and monthly gestational weight gain (MGWG) with maternal cardiometabolic risk indicators (total cholesterol, triglycerides, glucose, and blood pressure) during pregnancy. 720 women were included. Women with pre-gestational obesity had higher lipid concentrations initially, but these increased less than in normal-weight women. By the end of pregnancy, obese women had lower lipid concentrations. However, they had higher glucose and blood pressure levels throughout pregnancy. pBMI, but not MGWG, was significantly associated with cardiometabolic risk trajectories, suggesting pBMI is a more relevant predictor of adverse outcomes during pregnancy than MGWG.

Publisher

Nutrition and Diabetes

Published On

Nov 25, 2021

Authors

Luz Isabel Omaña-Guzmán, Luis Ortiz-Hernández, Mónica Ancira-Moreno, Vanesa Morales-Hernández, Marie S. O'Neill, Felipe Vadillo-Ortega

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