This open-label, pragmatic clinical trial randomized pregnant and postpartum women in Nigeria to usual care or AI-guided screening for left ventricular systolic dysfunction (LVSD). The AI-guided screening used digital stethoscope recordings and 12-lead electrocardiograms with AI predictions for LVSD. AI-enabled digital stethoscope screening improved LVSD diagnosis compared to usual care, while the 12-lead AI-ECG showed a similar but not statistically significant trend. No serious adverse events were reported.

Demilade A. Adedinsewo, Andrea Carolina Morales-Lara, Bosede B. Afolabi, Oyewole A. Kushimo, Amam C. Mbakwem, Kehinde F. Ibiyemi, James Ayodele Ogunmodede, Hadijat Olaide Raji, Sadiq H. Ringim, Abdullahi A. Habib, Sabiu M. Hamza, Okechukwu S. Ogah, Gbolahan Obajimi, Olugbenga Oluseun Saanu, Olusoji E. Jagun, Francisca O. Inofomoh, Temitope Adeolu, Kamilu M. Karaye, Sule A. Gaya, Isiaka Alfa, Cynthia Yohanna, K. L. Venkatachalam, Jennifer Dugan, Xiaoxi Yao, Hanna J. Sledge, Patrick W. Johnson, Mikolaj A. Wieczorek, Zachi I. Attia, Sabrina D. Phillips, Mohamad H. Yamani, Yvonne Butler Tobah, Carl H. Rose, Emily E. Sharpe, Francisco Lopez-Jimenez, Paul A. Friedman, Peter A. Noseworthy, Rickey E. Carter