This open-label, pragmatic clinical trial randomized pregnant and postpartum women in Nigeria to usual care or AI-guided screening for left ventricular systolic dysfunction (LVSD). AI-guided screening, using a digital stethoscope and 12-lead ECG with AI predictions, significantly improved LVSD diagnosis compared to usual care (digital stethoscope: odds ratio 2.12, P=0.032; 12-lead ECG: odds ratio 1.75, P=0.125). No serious adverse events were reported. AI-guided screening using a digital stethoscope improved the diagnosis of pregnancy-related cardiomyopathy.
Publisher
Nature Medicine
Published On
Oct 01, 2024
Authors
Demilade A. Adedinsewo, Andrea Carolina Morales-Lara, Bosede B. Afolabi, Oyewole A. Kushimo, Amam C. Mbakwem, Kehinde F. Ibiyemi, James Ayodele Ogunmodede, Hadijat Olaide Raji, Sadiq H. Ringim, Abdullahi A. Habib, Sabiu M. Hamza, Okechukwu S. Ogah, Gbolahan Obajimi, Olugbenga Oluseun Saanu, Olusoji E. Jagun, Francisca O. Inofomoh, Temitope Adeolu, Kamilu M. Karaye, Sule A. Gaya, Isiaka Alfa, Cynthia Yohanna, K. L. Venkatachalam, Jennifer Dugan, Xiaoxi Yao, Hanna J. Sledge, Patrick W. Johnson, Mikolaj A. Wieczorek, Zachi I. Attia, Sabrina D. Phillips, Mohamad H. Yamani, Yvonne Butler Tobah, Carl H. Rose, Emily E. Sharpe, Francisco Lopez-Jimenez, Paul A. Friedman, Peter A. Noseworthy, Rickey E. Carter
Tags
AI-guided screening
left ventricular systolic dysfunction
pregnancy-related cardiomyopathy
digital stethoscope
12-lead ECG
clinical trial
cardiovascular health
Related Publications
Explore these studies to deepen your understanding of the subject.
