Medicine and Health

Artificial intelligence guided screening for cardiomyopathies in an obstetric population: a pragmatic randomized clinical trial

D. A. Adedinsewo, A. C. Morales-lara, et al.

This groundbreaking clinical trial, conducted by a team of expert authors, reveals how AI-guided screening can significantly enhance the diagnosis of left ventricular systolic dysfunction (LVSD) in pregnant and postpartum women. Utilizing advanced technology, including digital stethoscopes and electrocardiograms, the study demonstrates promising results over usual care practices.

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Index

Abstract

This open-label, pragmatic clinical trial randomized pregnant and postpartum women in Nigeria to usual care or AI-guided screening for left ventricular systolic dysfunction (LVSD). The AI-guided screening used digital stethoscope recordings and 12-lead electrocardiograms with AI predictions for LVSD. AI-enabled digital stethoscope screening improved LVSD diagnosis compared to usual care, while the 12-lead AI-ECG showed a similar but not statistically significant trend. No serious adverse events were reported.

Publisher

Nature Medicine

Published On

Oct 01, 2024

Authors

Demilade A. Adedinsewo, Andrea Carolina Morales-Lara, Bosede B. Afolabi, Oyewole A. Kushimo, Amam C. Mbakwem, Kehinde F. Ibiyemi, James Ayodele Ogunmodede, Hadijat Olaide Raji, Sadiq H. Ringim, Abdullahi A. Habib, Sabiu M. Hamza, Okechukwu S. Ogah, Gbolahan Obajimi, Olugbenga Oluseun Saanu, Olusoji E. Jagun, Francisca O. Inofomoh, Temitope Adeolu, Kamilu M. Karaye, Sule A. Gaya, Isiaka Alfa, Cynthia Yohanna, K. L. Venkatachalam, Jennifer Dugan, Xiaoxi Yao, Hanna J. Sledge, Patrick W. Johnson, Mikolaj A. Wieczorek, Zachi I. Attia, Sabrina D. Phillips, Mohamad H. Yamani, Yvonne Butler Tobah, Carl H. Rose, Emily E. Sharpe, Francisco Lopez-Jimenez, Paul A. Friedman, Peter A. Noseworthy, Rickey E. Carter

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