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Alteration of NMDA receptor trafficking as a cellular hallmark of psychosis

Psychology

Alteration of NMDA receptor trafficking as a cellular hallmark of psychosis

A. Espana, H. Seth, et al.

This research by Agnès Espana and colleagues investigates how dysfunctions in NMDAR trafficking contribute to psychotic disorders like schizophrenia. By examining multiple models, the study reveals consistent alterations in hippocampal neurons and opens new therapeutic avenues through manipulations of NMDAR surface dynamics.

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