This study investigates the association between allergic conjunctivitis (AC), air pollution, and meteorological conditions in Northeast China (2014-2018). Results show a 7.6% annual increase in AC incidence, highest in provincial capitals. Incidence is positively correlated with PM2.5, PM10, CO, SO2, NO2, O3, air temperature, and wind speed, but negatively correlated with relative humidity. Threshold values for pollutants and meteorological factors were determined, some exceeding Chinese and WHO standards, highlighting environmental risks, particularly for SO2, NO2, and O3.