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Advanced Vaccine Design Strategies against SARS-CoV-2 and Emerging Variants

Medicine and Health

Advanced Vaccine Design Strategies against SARS-CoV-2 and Emerging Variants

J. Zhang, Y. Xia, et al.

This review sheds light on innovative vaccine strategies against SARS-CoV-2 and its variants. Authored by Jianzhong Zhang, Yutian Xia, Xuan Liu, and Gang Liu, it explores diverse vaccine types such as mRNA and viral vector vaccines, while also delving into novel approaches like structure-guided design and respiratory mucosal delivery.

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Playback language: English
Abstract
This review summarizes advanced vaccine design strategies against SARS-CoV-2 and its emerging variants. It discusses various vaccine types developed, including mRNA, viral vector, DNA, and subunit vaccines, highlighting their successes and limitations in combating the pandemic. The review focuses on novel strategies such as structure-guided vaccine design, T-cell-based vaccines, respiratory mucosal delivery, and nanotechnologies, analyzing their advantages and challenges. Finally, it addresses future directions in vaccine development, emphasizing the need for broader protection against evolving variants and improved vaccine accessibility.
Publisher
Bioengineering
Published On
Jan 22, 2023
Authors
Jianzhong Zhang, Yutian Xia, Xuan Liu, Gang Liu
Tags
SARS-CoV-2
vaccine design
mRNA vaccines
viral vector vaccines
emerging variants
nanotechnologies
vaccine accessibility

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