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Adipocytes control food intake and weight regain via Vacuolar-type H⁺ ATPase

Medicine and Health

Adipocytes control food intake and weight regain via Vacuolar-type H⁺ ATPase

R. C. Zapata, M. Carretero, et al.

This innovative study delves into the molecular mechanisms of weight regain after obesity-induced weight loss, revealing that 'metabolic memory' resides in adipocytes. Researchers highlighted *ATP6v0al*, a key regulator identified in a *C. elegans* screen, as a promising therapeutic target for obesity, based on findings from a team led by Rizaldy C. Zapata and Maria Carretero.

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