logo
ResearchBunny Logo
Accurate global and local 3D alignment of cryo-EM density maps using local spatial structural features

Computer Science

Accurate global and local 3D alignment of cryo-EM density maps using local spatial structural features

B. He, F. Zhang, et al.

Discover CryoAlign, a groundbreaking method developed by Bintao He, Fa Zhang, Chenjie Feng, Jianyi Yang, Xin Gao, and Renmin Han for precise alignment of cryo-EM density maps. This innovative approach harnesses local density features for quick and reliable alignment, outperforming existing techniques in both speed and accuracy.

00:00
00:00
Playback language: English
Abstract
This paper introduces CryoAlign, a novel method for accurate global and local alignment of cryo-EM density maps. CryoAlign leverages local density feature descriptors to capture spatial structural similarities, enabling fast and robust alignment parameter estimation. Extensive evaluations demonstrate its superiority over existing methods in terms of accuracy and speed.
Publisher
Nature Communications
Published On
Feb 21, 2024
Authors
Bintao He, Fa Zhang, Chenjie Feng, Jianyi Yang, Xin Gao, Renmin Han
Tags
Cryo-EM
density maps
global alignment
local alignment
feature descriptors
parameter estimation
accuracy

Related Publications

Explore these studies to deepen your understanding of the subject.

Spatial gradients of urban land density and nighttime light intensity in 30 global megacities
Environmental Studies and Forestry

Spatial gradients of urban land density and nighttime light intensity in 30 global megacities

M. Zheng, W. Huang, et al.

The cryo-EM structure of the bd oxidase from *M. tuberculosis* reveals a unique structural framework and enables rational drug design to combat TB
Medicine and Health

The cryo-EM structure of the bd oxidase from *M. tuberculosis* reveals a unique structural framework and enables rational drug design to combat TB

S. Safarian, H. K. Opel-reading, et al.

3D mechanical characterization of single cells and small organisms using acoustic manipulation and force microscopy
Biology

3D mechanical characterization of single cells and small organisms using acoustic manipulation and force microscopy

N. F. Läubli, J. T. Burri, et al.

TomoTwin: generalized 3D localization of macromolecules in cryo-electron tomograms with structural data mining
Biology

TomoTwin: generalized 3D localization of macromolecules in cryo-electron tomograms with structural data mining

G. Rice, T. Wagner, et al.

Listen, Learn & Level Up
Over 10,000 hours of research content in 25+ fields, available in 12+ languages.
No more digging through PDFs, just hit play and absorb the world's latest research in your language, on your time.
listen to research audio papers with researchbunny