This paper introduces a skin-mountable electrostimulation-augmented photothermal patch (eT-patch) for melanoma treatment. The eT-patch, composed of a transparent ionic gel doped with MXene (Ti3C2Tx), exhibits superior photothermal and electrical characteristics. Under photostimulation, the eT-patch synergistically triggers cancer cell apoptosis and pyroptosis, leading to melanoma cell death. Its good biocompatibility and minimal side effects make it a promising therapeutic strategy for skin tumors.
