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Abstract
This paper introduces a visible light-responsive azo-fluorescent switch that can be monitored via fluorescence imaging. Visible light irradiation triggers isomerization, altering fluorescence and enabling imaging-based tracking. The study demonstrates that liposome-encapsulated nanoparticles containing this azo switch exhibit nanocavity size changes during isomerization, facilitating the creation of a light-responsive nanoplatform for controlled antimycotic release. Natural light activation of these nanoparticles carrying an antimycotic agent effectively kills *Rhizoctonia solani*, extending the holding period compared to small-molecule antimycotics. This strategy offers a potentially widely applicable approach for controlled drug delivery.
Publisher
Nature Communications
Published On
Oct 07, 2024
Authors
Yurou Huang, Xiaoyan Zeng, Xiaoxie Ma, Zibo Lin, Jiayue Sun, Wang Xiao, Sheng Hua Liu, Jun Yin, Guang-Fu Yang
Tags
azo-fluorescent switch
fluorescence imaging
nanoparticles
light-responsive
antimycotic release
controlled drug delivery
isomerization

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