Chemistry

A synthetic cell-free 36-enzyme reaction system for vitamin B<sub>12</sub> production

Q. Kang, H. Fang, et al.

Discover a groundbreaking method for synthesizing adenosylcobalamin (AdoCbl), a vital form of vitamin B12, using a cell-free reaction system. This innovative approach, developed by Qian Kang, Huan Fang, Mengjie Xiang, Kaixing Xiao, Pingtao Jiang, Chun You, Sang Yup Lee, and Dawei Zhang, promises to revolutionize the production of complex natural compounds by utilizing inexpensive 5-aminolevulinic acid.

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