BiologyPNAS
A synapse-specific refractory period for plasticity at individual dendritic spines
J. C. Flores, D. Sarkar, et al.
Recently potentiated individual synapses enter a synapse-specific refractory period that limits further potentiation until key postsynaptic proteins recover — a process linked to reduced CaMKII signaling and reversible by raising PSD95. Research was conducted by Juan C. Flores, Dipannita Sarkar, and Karen Zito.
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