Medicine and Health

A Gamma-adapted subunit vaccine induces broadly neutralizing antibodies against SARS-CoV-2 variants and protects mice from infection

L. M. Coria, J. M. Rodriguez, et al.

A groundbreaking study by Lorena M. Coria and colleagues reveals that a Gamma SARS-CoV-2 variant RBD vaccine adjuvanted with Alum is significantly more immunogenic than traditional options. This vaccine not only induces broader neutralizing antibodies but also enhances T cell responses, offering robust protection against various SARS-CoV-2 challenges. Its performance as a heterologous booster holds promise for future vaccinations.