Medicine and Health

3D microfluidic gradient generator for combination antimicrobial susceptibility testing

E. Sweet, B. Yang, et al.

This groundbreaking research explores the limitations of traditional 2D microfluidic concentration gradient generators in antimicrobial susceptibility testing by introducing a novel 3D-printed microchannel network. The team evaluated the antimicrobial effects of tetracycline, ciprofloxacin, and amikacin against antibiotic-resistant E. coli, paving the way for faster combination AST screening. This innovative platform was developed by authors Eric Sweet, Brenda Yang, Joshua Chen, Reed Vickerman, Yujui Lin, Alison Long, Eric Jacobs, Tinglin Wu, Camille Mercier, Ryan Jew, Yash Attal, Siyang Liu, Andrew Chang, and Liwei Lin.... show more

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