UltraSound-induced reorientation for multi-angle optical | ResearchBunny

Index

Abstract

Optical coherence tomography (OCT) is a valuable tool for monitoring organoids and spheroids, but mature specimens can be too opaque. This paper presents ULTIMA-OCT, a method using ultrasound-induced reorientation to acquire multi-angle OCT images. A 3D-printed acoustic trap levitates and rotates samples, enabling 3D tomographic reconstruction of reflectivity, attenuation, refractive index, and position, even for optically dense samples. A model-based algorithm fuses data from a priori unknown angles, demonstrating enhanced penetration depth in zebrafish larvae.

Publisher

Nature Communications

Published On

Mar 16, 2024

Authors

Mia Kvåle Løvmo, Shiyu Deng, Simon Moser, Rainer Leitgeb, Wolfgang Drexler, Monika Ritsch-Marte

Related Publications

Explore these studies to deepen your understanding of the subject.

Medicine and Health

Ultrathin monolithic 3D printed optical coherence tomography endoscopy for preclinical and clinical use

J. Li, S. Thiele, et al.

Medicine and Health

Liquid-shaped microlens for scalable production of ultrahigh-resolution optical coherence tomography microendoscope

C. Xu, X. Guan, et al.

Engineering and Technology

Massively parallel electro-optic sampling of space-encoded optical pulses for ultrafast multi-dimensional imaging

Y. Na, H. Kwak, et al.

Medicine and Health

Toward optical coherence tomography on a chip: in vivo three-dimensional human retinal imaging using photonic integrated circuit-based arrayed waveguide gratings

E. A. Rank, R. Sentosa, et al.

Listen, Learn & Level Up

Over 10,000 hours of research content in 25+ fields, available in 12+ languages.

No more digging through PDFs—just hit play and absorb the world's latest research in your language, on your time.

listen to research audio papers with researchbunny