Medicine and Health

Transplacental transmission of SARS-CoV-2 infection

A. J. Vivanti, C. Vauloup-fellous, et al.

This groundbreaking research reveals the transplacental transmission of SARS-CoV-2 from mother to neonate during the crucial last trimester of pregnancy. The findings document a correlation between maternal viremia and alarming neurological symptoms in the newborn, confirmed through advanced virological and pathological investigations. Discover the implications of this work by Alexandre J. Vivanti and colleagues.

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Abstract

This paper demonstrates the transplacental transmission of SARS-CoV-2 from a mother to her neonate in the last trimester of pregnancy. The neonate presented with neurological compromise. The transmission is confirmed through virological and pathological investigations, showing maternal viremia, placental infection with high viral load and inflammation, and subsequent neonatal viremia. The neonate exhibited neurological manifestations similar to those seen in adults with COVID-19.

Publisher

NATURE COMMUNICATIONS

Published On

Jul 14, 2020

Authors

Alexandre J. Vivanti, Christelle Vauloup-Fellous, Sophie Prevot, Veronique Zupan, Cecile Suffee, Jeremy Do Cao, Alexandra Benachi, Daniele De Luca

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