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The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer

Medicine and Health

The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer

N. Ghaddar, S. Wang, et al.

Discover how the integrated stress response (ISR) plays a critical role in lung adenocarcinoma development, influencing tumor growth and invasiveness. This insightful research led by Nour Ghaddar and colleagues reveals the potential of ISR inhibitors as a promising therapeutic avenue for KRAS-driven lung cancer.

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