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The human VGLUT3-pT8I mutation elicits uneven striatal DA signaling, food or drug maladaptive consumption in male mice

Medicine and Health

The human VGLUT3-pT8I mutation elicits uneven striatal DA signaling, food or drug maladaptive consumption in male mice

M. Favier, E. M. Garcia, et al.

This groundbreaking research by Mathieu Favier and colleagues delves into the role of VGLUT3 in cholinergic striatal interneurons, exploring its impact on addiction and eating disorders. Discover how the VGLUT3-p.T8I variant leads to altered dopaminergic transmission and how enhancing acetylcholine could reverse self-starvation behaviors. A must-listen for anyone interested in the neurochemical underpinnings of substance use and food habits!

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