Medicine and HealthFrontiers in Neuroscience

The effects of sleep deprivation on cognitive flexibility: a scoping review of outcomes and biological mechanisms

X. Sun, Z. Qu, et al.

Sleep deprivation—particularly total sleep loss—appears to impair cognitive flexibility and task‑switching accuracy, with mechanisms likely involving reduced cerebral oxygen supply, impaired cerebrovascular reactivity, and hormonal and gene‑expression changes. Evidence for partial sleep loss is mixed and overweight status may worsen effects. More rigorous trials with objective measures are needed. This research was conducted by Xuefeng Sun, Zihan Qu, Xiaotu Zhang, Ye Zhang, Xinye Zhang, Haifeng Zhao, and Hongshi Zhang.... show more

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