Medicine and Health

The effect of exercise on blood concentrations of angiogenesis markers in older adults: a systematic review and meta-analysis

B. X. Song, L. Azhar, et al.

Discover the transformative power of exercise on vascular health in older adults! This meta-analysis reveals that exercise boosts vascular endothelial growth factor (VEGF) levels while reducing e-selectin (CD62E). Conducted by a team of experts including Bing Xin Song and Laiba Azhar, this research sheds light on how exercise-induced changes in angiogenesis markers may enhance health outcomes in seniors.

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Playback language: English

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Abstract

This meta-analysis and systematic review investigated the effects of exercise on peripheral angiogenesis markers in older adults. MEDLINE, Embase, and Cochrane CENTRAL were searched for relevant studies. Vascular endothelial growth factor (VEGF) was found to be higher after exercise, and e-selectin (CD62E) was lower. Endostatin, fibroblast growth factor 2 (FGF2), and matrix metallopeptidase-9 (MMP9) levels did not change. Changes in angiogenesis markers may explain the beneficial effects of exercise on angiogenesis and health in older adults.

Publisher

This preprint is not yet published in a journal

Published On

Jan 16, 2023

Authors

Bing Xin Song, Laiba Azhar, Grace Ka, Yi Koo, Susan Marzolini, Damien Gallagher, Walter Swardfager, Clara Chen, Joycelyn Ba, Nathan Herrmann, Krista Lanctôt

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