This meta-analysis and systematic review investigated the effects of exercise on peripheral angiogenesis markers in older adults. MEDLINE, Embase, and Cochrane CENTRAL were searched for relevant studies. Vascular endothelial growth factor (VEGF) was found to be higher after exercise, and e-selectin (CD62E) was lower. Endostatin, fibroblast growth factor 2 (FGF2), and matrix metallopeptidase-9 (MMP9) levels did not change. Changes in angiogenesis markers may explain the beneficial effects of exercise on angiogenesis and health in older adults.
Publisher
This preprint is not yet published in a journal
Published On
Jan 16, 2023
Authors
Bing Xin Song, Laiba Azhar, Grace Ka, Yi Koo, Susan Marzolini, Damien Gallagher, Walter Swardfager, Clara Chen, Joycelyn Ba, Nathan Herrmann, Krista Lanctôt
Tags
exercise
peripheral angiogenesis
older adults
vascular health
VEGF
e-selectin
health benefits
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