Medicine and Health

The burden of diabetes-associated multiple long-term conditions on years of life spent and lost

E. W. Gregg, A. Pratt, et al.

This groundbreaking study reveals that diabetes significantly accelerates the onset of severe multiple long-term conditions, with dramatic implications for 46 million English adults. Conducted by a team of experts including Edward W. Gregg and Adrian Pratt, it emphasizes the urgent need for enhanced prevention and management strategies to combat this escalating health crisis.

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Playback language: English

Index

Abstract

This study investigated the burden of diabetes-related multiple long-term conditions (MLTCs) in 46 million English adults. It found that diabetes accelerates the onset of severe MLTCs by 20 years in women and 15 years in men. By age 50, one-third of those with diabetes have at least three conditions, experience them for over 20 years, and die 11 years earlier than the general population. Hypertension, depression, cancer, and coronary heart disease were major contributors in older adults, while depression, severe mental illness, learning disabilities, alcohol dependence, and asthma played larger roles in younger adults. These findings highlight the need for improved prevention and management strategies.

Publisher

Nature Medicine

Published On

Aug 01, 2024

Authors

Edward W. Gregg, Adrian Pratt, Alex Owens, Emma Barron, Rupert Dunbar-Rees, Eirion T. Slade, Nasrin Hafezparast, Chirag Bakhai, Paul Chappell, Victoria Cornelius, Desmond G. Johnston, Jacqueline Mathews, Jason Pickles, Ellie Bragan Turner, Gary Wainman, Kate Roberts, Kamlesh Khunti, Jonathan Valabhji

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