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Target engagement and immunogenicity of an active immunotherapeutic targeting pathological α-synuclein: a phase 1 placebo-controlled trial

Medicine and Health

Target engagement and immunogenicity of an active immunotherapeutic targeting pathological α-synuclein: a phase 1 placebo-controlled trial

P. Eijsvogel, P. Misra, et al.

This groundbreaking 44-week study explores UB-312, an innovative immunotherapeutic approach targeting pathological αSyn in Parkinson's disease patients. With safety and immunogenicity confirmed, findings indicate a significant reduction in αSyn seeds, paving the way for further development. Conducted by a team of experts, these promising results are a step forward in Parkinson's research.

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