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Structure and rational engineering of the PgIX methyltransferase and specificity factor for BREX phage defence

Biology

Structure and rational engineering of the PgIX methyltransferase and specificity factor for BREX phage defence

S. C. Went, D. M. Picton, et al.

This exciting study by Sam C. Went and colleagues dives into the intricate world of *Salmonella* BREX systems, revealing how they harness X-ray crystal structures to ward off bacteriophages. Discover the fascinating mechanisms of DNA binding and the potential for rational engineering to enhance phage targeting!

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