Stronger gut microbiome modulatory effects by postbiotics than | ResearchBunny

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Abstract

This study compared the effects of probiotics and postbiotics derived from *Bifidobacterium adolescentis* B8589 in a mouse colitis model. Both improved colitis symptoms (decreased histology scores), but postbiotics showed stronger effects on modulating fecal microbiota beta diversity, composition, and metagenomic potential. The authors suggest postbiotics are a safer and more effective alternative to probiotics for managing ulcerative colitis.

Publisher

npj Science of Food

Published On

Nov 15, 2022

Authors

Tao Zhang, Weiqin Zhang, Cuijiao Feng, Lai-Yu Kwok, Qiuwen He, Zhihong Sun

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