Health and Fitness

Risk of yellow fever virus transmission in the Asia-Pacific region

L. D. G. D. Lataillade, M. Vazeille, et al.

This groundbreaking study reveals that *Aedes* mosquitoes in the Asia-Pacific region can transmit Yellow Fever Virus, raising concerns about potential outbreaks. Conducted by a team of experts including Lucy de Guilhem de Lataillade and Marie Vazeille from Institut Pasteur, the findings indicate that *Aedes aegypti* can excrete significant viral loads, highlighting a critical public health risk.

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Abstract

Historically endemic to Sub-Saharan Africa and South America, yellow fever is absent from the Asia-Pacific region. This study investigates the vector competence of Asian-Pacific *Aedes* mosquitoes for Yellow Fever Virus (YFV). Experimental infections show that *Aedes aegypti* populations from Singapore, Taiwan, Thailand, and New Caledonia can transmit YFV, with saliva excretion reaching up to 23,000 viral particles. *Aedes albopictus* showed lower competence. These findings highlight a significant risk of YFV emergence in the Asia-Pacific region.

Publisher

Nature Communications

Published On

Nov 16, 2020

Authors

Lucy de Guilhem de Lataillade, Marie Vazeille, Thomas Obadia, Yoann Madec, Laurence Mousson, Basile Kamgang, Chun-Hong Chen, Anna-Bella Failloux, Pei-Shi Yen

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