Medicine and Health

Repurposing of known drugs for COVID-19 using molecular docking and simulation analysis

P. Bhanu, A. S. Setlur, et al.

This research delves into repurposing 51 existing drugs for COVID-19 treatment, uncovering potential drug candidates with strong binding affinities for key proteins involved in SARS-CoV-2 infection. The study reveals exciting prospects for further clinical investigation by an expert team including Piyush Bhanu and Anagha S Setlur.

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Index

Abstract

This research investigated the repurposing of 51 existing drugs for COVID-19 treatment. Using molecular docking and simulation analysis, the study focused on five key protein targets involved in SARS-CoV-2 infection. The findings revealed several drug candidates with strong binding affinities and stable interactions, suggesting potential for further clinical investigation.

Publisher

Bioinformation

Published On

Feb 28, 2023

Authors

Piyush Bhanu, Anagha S Setlur, K Chandrashekar, Vidya Niranjan, Nisha Hemandhar Kumar, Sakshi Buchke, Jitendra Kumar, Anita Rani, Sushil M Tiwari, Vachaspati Mishra

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