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Real-time, selective, and low-cost detection of trace level SARS-CoV-2 spike-protein for cold-chain food quarantine

Food Science and Technology

Real-time, selective, and low-cost detection of trace level SARS-CoV-2 spike-protein for cold-chain food quarantine

J. Zhang, X. Fang, et al.

Discover a groundbreaking method for real-time detection of trace-level SARS-CoV-2 spike protein in cold-chain foods, developed by an expert team of researchers. With a limit of detection as low as 2.29 × 10⁻¹⁰ ng/mL in just 20 seconds, this innovative approach promises efficient and cost-effective screening solutions for food safety.

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Playback language: English
Abstract
This paper presents a novel strategy for the real-time, selective, and low-cost detection of trace-level SARS-CoV-2 spike protein in cold-chain foods. The method utilizes a modified interdigitated microelectrode chip, dielectrophoresis enrichment, and interfacial capacitance sensing to achieve a limit of detection as low as 2.29 × 10⁻¹⁰ ng/mL within 20 seconds. The method exhibits a wide linear range (10⁻⁵-10⁻¹ ng/mL) and high selectivity (234:1), while the cost per test is approximately $1. This technology offers a promising solution for large-scale screening in cold-chain food quarantine.
Publisher
npj Science of Food
Published On
Jun 01, 2021
Authors
Jian Zhang, Xin Fang, Yu Mao, Haochen Qi, Jayne Wu, Xiaoru Liu, Fangshuo You, Wenci Zhao, Ying Chen, Lei Zheng
Tags
SARS-CoV-2
spike protein
cold-chain foods
detection method
dielectrophoresis
microelectrode chip
food safety
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