Food Science and Technology

Real-time, selective, and low-cost detection of trace level SARS-CoV-2 spike-protein for cold-chain food quarantine

J. Zhang, X. Fang, et al.

Discover a groundbreaking method for real-time detection of trace-level SARS-CoV-2 spike protein in cold-chain foods, developed by an expert team of researchers. With a limit of detection as low as 2.29 × 10⁻¹⁰ ng/mL in just 20 seconds, this innovative approach promises efficient and cost-effective screening solutions for food safety.

00:00

Playback language: English

Index

Abstract

This paper presents a novel strategy for the real-time, selective, and low-cost detection of trace-level SARS-CoV-2 spike protein in cold-chain foods. The method utilizes a modified interdigitated microelectrode chip, dielectrophoresis enrichment, and interfacial capacitance sensing to achieve a limit of detection as low as 2.29 × 10⁻¹⁰ ng/mL within 20 seconds. The method exhibits a wide linear range (10⁻⁵-10⁻¹ ng/mL) and high selectivity (234:1), while the cost per test is approximately $1. This technology offers a promising solution for large-scale screening in cold-chain food quarantine.

Publisher

npj Science of Food

Published On

Jun 01, 2021

Authors

Jian Zhang, Xin Fang, Yu Mao, Haochen Qi, Jayne Wu, Xiaoru Liu, Fangshuo You, Wenci Zhao, Ying Chen, Lei Zheng

Related Publications

Explore these studies to deepen your understanding of the subject.

Medicine and Health

Risk factors for and pregnancy outcomes after SARS-CoV-2 in pregnancy according to disease severity: A nationwide cohort study with validation of the SARS-CoV-2 diagnosis of Nordic Federation of Societies of Obstetrics and Gynecology (NFOG)

A. J. M. Aabakke, T. G. Petersen, et al.

Medicine and Health

Histones released by NETosis enhance the infectivity of SARS-CoV-2 by bridging the spike protein subunit 2 and sialic acid on host cells

W. Hong, J. Yang, et al.

Medicine and Health

Emergence and spread of a SARS-CoV-2 lineage A variant (A.23.1) with altered spike protein in Uganda

D. L. Bugembe, M. V. T. Phan, et al.

Medicine and Health

Broad host range of SARS-CoV-2 and the molecular basis for SARS-CoV-2 binding to cat ACE2

L. Wu, Q. Chen, et al.

Listen, Learn & Level Up

Over 10,000 hours of research content in 25+ fields, available in 12+ languages.

No more digging through PDFs, just hit play and absorb the world's latest research in your language, on your time.

listen to research audio papers with researchbunny