Medicine and Health

Real-time motion-enabling positron emission tomography of the brain of upright ambulatory humans

N. K. Siva, C. Bauer, et al.

Explore groundbreaking advancements in neuroimaging! This study introduces the Ambulatory Motion-enabling Positron Emission Tomography (AMPET) helmet system, showcasing its ability to capture brain activity during upright motion and walking. Conducted by notable researchers including Nanda K. Siva and Christopher Bauer, this research opens new avenues in real-world paradigms for brain imaging.

00:00

Playback language: English

Index

Abstract

Current human brain imaging methods are limited by not allowing both natural upright motion and deep brain coverage. This study tests the feasibility of an upright, motion-compatible brain imager, the Ambulatory Motion-enabling Positron Emission Tomography (AMPET) helmet system, for neuroimaging studies of human walking. Eleven participants performed a walking-in-place task with simultaneous AMPET imaging after receiving a bolus of 18F-Fluorodeoxyglucose. Results validated predetermined criteria, including brain alignment artifact <2 mm and functional neuroimaging outcomes consistent with existing walking movement literature. The study extends the potential of mobile, upright, and motion-tolerant neuroimaging devices in real-world paradigms.

Publisher

Communications Medicine

Published On

Jun 13, 2024

Authors

Nanda K. Siva, Christopher Bauer, Colson Glover, Alexander Stolin, Sonia Chandi, Helen Melnick, Gary Marano, Benjamin Parker, MaryBeth Mandich, James W. Lewis, Jinyi Qi, Si Gao, Kaylee Nott, Stan Majewski, Julie A. Brefczynski-Lewis

DOI

https://doi.org/10.1038/s43856-024-00547-2

Related Publications

Explore these studies to deepen your understanding of the subject.

Medicine and Health

A fluorescent sensor for real-time measurement of extracellular oxytocin dynamics in the brain

D. Ino, Y. Tanaka, et al.

Earth Sciences

Near-real-time monitoring of global CO2 emissions reveals the effects of the COVID-19 pandemic

Z. Liu, P. Ciais, et al.

Physics

Real-time microscopy of the relaxation of a glass

M. Ruiz-ruiz, A. Vila-costa, et al.

Chemistry

Element- and enantiomer-selective visualization of molecular motion in real-time

R. Mincigrucci, J. R. Rouxel, et al.

Listen, Learn & Level Up

Over 10,000 hours of research content in 25+ fields, available in 12+ languages.

No more digging through PDFs, just hit play and absorb the world's latest research in your language, on your time.

listen to research audio papers with researchbunny