Psychology

Psychotherapy with Psilocybin for Depression: Systematic Review

D. Hristova and Pérez-jover

This systematic review by Dawood Hristova and Pérez-Jover reveals the promising effects of psilocybin-assisted psychotherapy in alleviating depression. The findings suggest notable and lasting improvements in depressive symptoms, even among treatment-resistant patients, highlighting the pivotal role of therapists in this transformative process. Discover the potential of psychedelics in mental health!

00:00

Playback language: English

Index

Abstract

This systematic review examines the efficacy of psilocybin-assisted psychotherapy in treating depression. Eight studies were included, revealing significant and sustained reductions in depressive symptoms after one or two psilocybin sessions, even in treatment-resistant cases. The role of the therapist in establishing a therapeutic alliance and integrating the psychedelic experience is highlighted. While adverse effects were generally mild and transient, limitations include a small number of studies, geographic bias, and potential expectancy effects. Future research should explore different psychotherapy approaches and the role of spiritual experiences.

Publisher

Behav. Sci.

Published On

Mar 31, 2023

Authors

Dawood Hristova, Pérez-Jover

Related Publications

Explore these studies to deepen your understanding of the subject.

Psychology

Probiotics as a Tool for Regulating Molecular Mechanisms in Depression: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

A. Pinhasov, M. Sikorska, et al.

Psychology

Psychobiotic interventions for anxiety in young people: a systematic review and meta-analysis, with youth consultation

K. C. Kadosh, M. Basso, et al.

Medicine and Health

Effectiveness, Acceptability and Feasibility of Technology-Enabled Health Interventions for Adolescents Living with HIV in Low-and Middle-Income Countries: A Systematic Review

P. B. Tchounwou, C. A. Latkin, et al.

Psychology

Psilocybin for treatment-resistant depression without psychedelic effects: study protocol for a 4-week, double-blind, proof-of-concept randomised controlled trial

M. I. Husain, D. M. Blumberger, et al.

Listen, Learn & Level Up

Over 10,000 hours of research content in 25+ fields, available in 12+ languages.

No more digging through PDFs, just hit play and absorb the world's latest research in your language, on your time.

listen to research audio papers with researchbunny