Chemistry

Porous carbon nanowire array for surface-enhanced Raman spectroscopy

N. Chen, T. Xiao, et al.

Discover the revolutionary porous carbon nanowire array (PCNA) that enhances Raman spectroscopy, making it a game-changer in biomedical applications. This innovative, metal-free substrate tackles issues of reproducibility, biocompatibility, and durability, achieving signal enhancements of up to ~10⁶. Explore the findings of this groundbreaking research conducted by the team of authors from The University of Tokyo and other institutions.

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Abstract

Surface-enhanced Raman spectroscopy (SERS) is a powerful tool for vibrational spectroscopy, but its reliability in biomedical applications is hampered by reproducibility, uniformity, biocompatibility, and durability issues. This article demonstrates a metal-free, topologically tailored nanostructure—a porous carbon nanowire array (PCNA)—as a SERS substrate to overcome these problems. The PCNA offers high signal enhancement (~10⁶) due to broadband charge-transfer resonance, high reproducibility due to the absence of hot spots, high durability due to no oxidation, and high biocompatibility due to fluorescence quenching. Experiments with various molecules confirm its excellent properties, making it highly reliable for practical use in various fields.

Publisher

Nature Communications

Published On

Sep 24, 2020

Authors

Nan Chen, Ting-Hui Xiao, Zhenyi Luo, Yasutaka Kitahama, Kotaro Hiramatsu, Naoki Kishimoto, Tamitake Itoh, Zhenzhou Cheng, Keisuke Goda

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