Patterns of brain asymmetry associated with polygenic risks for | ResearchBunny

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Abstract

This study investigated the multivariate associations of polygenic risk scores for autism spectrum disorder (ASD) and schizophrenia with brain asymmetries in 32,256 UK Biobank participants. Results showed distinct patterns of brain asymmetry associated with each disorder, implicating language and executive functions but not supporting the hypothesis of brain masculinization or feminization in their etiologies.

Publisher

Molecular Psychiatry

Published On

Jul 01, 2021

Authors

Zhiqiang Sha, Dick Schijven, Clyde Francks

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