Psychology

Patterns of activity correlate with symptom severity in major depressive disorder patients

S. Spulber, F. Elberling, et al.

This study explores the intriguing link between activity patterns and depression symptom severity in patients with major depressive disorder not on antidepressants. The research, conducted by S. Spulber, F. Elberling, J. Svensson, M. Tiger, S. Ceccatelli, and J. Lundberg, unveils that higher depression severity is tied to simpler activity patterns and a stronger reliance on external factors, highlighting actigraphy's potential in evaluating MDD patients.

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Abstract

This study investigates the correlation between activity patterns and depression symptom severity in patients with major depressive disorder (MDD) not undergoing antidepressant treatment. Using actigraphy data from two independent studies, the researchers trained multiple regression models to predict the Montgomery-Åsberg Depression Rating Scale (MADRS) score from activity pattern features. Results suggest that higher symptom severity is associated with less complex activity patterns and stronger coupling to external circadian entrainers. Actigraphy may be a useful tool for evaluating MDD patients.

Publisher

Translational Psychiatry

Published On

Jun 02, 2022

Authors

S. Spulber, F. Elberling, J. Svensson, M. Tiger, S. Ceccatelli, J. Lundberg

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