Biology

Parallel processing of past and future memories through reactivation and synaptic plasticity mechanisms during sleep

K. Ghandour, T. Haga, et al.

Everyday memories emerge from organized hippocampal activity: in male mice, CA1 neurons show synchronous prelearning sleep patterns that align with future engram cells (preconfigured ensembles), while postlearning offline periods reshape nonengram cells via potential synaptic depression and scaling to prepare for new memories. This research was conducted by Authors present in <Authors> tag.