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Near-complete genome of SARS-CoV-2 Delta variant of concern identified in a symptomatic dog (Canis lupus familiaris) in Botswana

Veterinary Science

Near-complete genome of SARS-CoV-2 Delta variant of concern identified in a symptomatic dog (Canis lupus familiaris) in Botswana

W. T. Choga, S. L. Letsholo, et al.

This groundbreaking case report reveals the first recorded instance of SARS-CoV-2 infection in a dog in Botswana, highlighting crucial findings from a 5-year-old crossbreed dog that tested positive for the virus. The study emphasizes the importance of monitoring pets during COVID-19 outbreaks, conducted by a team of experts including Wonderful T Choga and Samantha L Letsholo.

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Playback language: English
Abstract
This case report details the first documented instance of SARS-CoV-2 infection in a dog in Botswana. A 5-year-old male crossbreed dog exhibiting flu-like symptoms tested positive for SARS-CoV-2. Next-generation sequencing revealed a near-full-length SARS-CoV-2 genome (∼90% coverage) classified as a sublineage of the Delta variant. Phylogenetic analysis showed a close relationship to human Delta variant sequences circulating concurrently. The study highlights the need for monitoring pets during COVID-19 outbreaks.
Publisher
Veterinary Medicine and Science
Published On
Aug 03, 2023
Authors
Wonderful T Choga, Samantha L Letsholo, Chandapiwa Marobela-Raborokgwe, Irene Gobe, Mbatshi Mazwiduma, Dorcas Maruapula, John Rukwava, Mary Gorettie Binta, Boitumelo J L Zuze, Legodile Koopile, Kedumetse Seru, Patience Motshosi, Ontlametse Thato Bareng, Botshelo Radibe, Pamela Smith-Lawrence, Kutlo Macheke, Lesego Kuate-Lere, Modisa S Motswaledi, Mpaphi B Mbulawa, Mogomotsi Matshaba, Kereng V Masupu, Shahin Lockman, Roger Shapiro, Joseph Makhema, Mosepele Mosepele, Simani Gaseitsiwe, Sikhulile Moyo
Tags
SARS-CoV-2
dog infection
Botswana
Delta variant
COVID-19 monitoring
next-generation sequencing
phylogenetic analysis

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