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Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission

Medicine and Health

Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission

H. Peckham, N. M. D. Gruijter, et al.

This groundbreaking meta-analysis reveals a concerning global trend in COVID-19 outcomes – while infection rates are similar between sexes, males are nearly three times more likely to require intensive treatment and face greater odds of death compared to females. Insights from this research conducted by Hannah Peckham, Nina M de Gruijter, Charles Raine, Anna Radziszewska, Coziana Ciurtin, Lucy R Wedderburn, Elizabeth C Rosser, Kate Webb, and Claire T Deakin could significantly impact clinical practices and health strategies worldwide.

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Playback language: English
Abstract
This meta-analysis of 3,111,714 global COVID-19 cases reveals that while there's no sex difference in infection rates, males have almost three times the odds of needing intensive treatment (OR=2.84) and higher odds of death (OR=1.39) compared to females. This sex bias is a global phenomenon with implications for clinical management and mitigation strategies.
Publisher
Nature Communications
Published On
Dec 09, 2020
Authors
Hannah Peckham, Nina M de Gruijter, Charles Raine, Anna Radziszewska, Coziana Ciurtin, Lucy R Wedderburn, Elizabeth C Rosser, Kate Webb, Claire T Deakin
Tags
COVID-19
gender differences
intensive treatment
mortality rates
sex bias

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