logo
ResearchBunny Logo
MALDI-TOF MS and genomic analysis can make the difference in the clarification of canine brucellosis outbreaks

Veterinary Science

MALDI-TOF MS and genomic analysis can make the difference in the clarification of canine brucellosis outbreaks

D. A. V. D. Silva, H. Brendebach, et al.

This fascinating study conducted by David Attuy Vey da Silva and colleagues delves into canine brucellosis, revealing its zoonotic threat and tracking an outbreak at a breeding kennel. Using advanced techniques like MALDI-TOF MS for quick species identification and whole-genome sequencing for insight into the outbreak's epidemiology, the researchers uncovered a unique sub-lineage of *Brucella canis* linked to strains in Central and South America.

00:00
00:00
Playback language: English
Abstract
Canine brucellosis, primarily caused by *Brucella canis*, poses a zoonotic threat. This study investigated a breeding kennel with brucellosis-like symptoms, using MALDI-TOF MS for rapid species identification and whole-genome sequencing for detailed outbreak analysis. MALDI-TOF MS quickly identified *B. canis*, distinguishing it from closely related *B. suis*. Genomic analysis revealed a distinct sub-lineage, clustering isolates with strains from Central and South America, indicating an endemic situation. The combined approach facilitated rapid identification and clarified the outbreak's epidemiology.
Publisher
Scientific Reports
Published On
Nov 06, 2020
Authors
David Attuy Vey da Silva, Holger Brendebach, Josephine Grützke, Ralf Dieckmann, Rodrigo Martins Soares, Julia Teresa Ribeiro de Lima, Lara Borges Keid, Dirk Hofreuter, Sascha Al Dahouk
Tags
canine brucellosis
Brucella canis
zoonotic disease
MALDI-TOF MS
whole-genome sequencing
outbreak analysis
epidemiology

Related Publications

Explore these studies to deepen your understanding of the subject.

Identification and quantitation of the actual active components in bamboo juice and its oral liquid by NMR and UPLC-Q-TOF-MS
Food Science and Technology

Identification and quantitation of the actual active components in bamboo juice and its oral liquid by NMR and UPLC-Q-TOF-MS

Q. Gao, D. Wang, et al.

Influence of social determinants of health in the evolution of the quality of life of older adults in Europe: A comparative analysis between men and women
Health and Fitness

Influence of social determinants of health in the evolution of the quality of life of older adults in Europe: A comparative analysis between men and women

R. Llorens-ortega, C. Bertran-noguer, et al.

Populism, cyberdemocracy and disinformation: analysis of the social media strategies of the French extreme right in the 2014 and 2019 European elections
Political Science

Populism, cyberdemocracy and disinformation: analysis of the social media strategies of the French extreme right in the 2014 and 2019 European elections

U. Carral, J. Tuñón, et al.

Monkeypox outbreaks in the context of the COVID-19 pandemic: Network and clustering analyses of global risks and modified SEIR prediction of epidemic trends
Medicine and Health

Monkeypox outbreaks in the context of the COVID-19 pandemic: Network and clustering analyses of global risks and modified SEIR prediction of epidemic trends

S. Luo, Jg, et al.

Listen, Learn & Level Up
Over 10,000 hours of research content in 25+ fields, available in 12+ languages.
No more digging through PDFs, just hit play and absorb the world's latest research in your language, on your time.
listen to research audio papers with researchbunny