Canine brucellosis, primarily caused by *Brucella canis*, poses a zoonotic threat. This study investigated a breeding kennel with brucellosis-like symptoms, using MALDI-TOF MS for rapid species identification and whole-genome sequencing for detailed outbreak analysis. MALDI-TOF MS quickly identified *B. canis*, distinguishing it from closely related *B. suis*. Genomic analysis revealed a distinct sub-lineage, clustering isolates with strains from Central and South America, indicating an endemic situation. The combined approach facilitated rapid identification and clarified the outbreak's epidemiology.
Publisher
Scientific Reports
Published On
Nov 06, 2020
Authors
David Attuy Vey da Silva, Holger Brendebach, Josephine Grützke, Ralf Dieckmann, Rodrigo Martins Soares, Julia Teresa Ribeiro de Lima, Lara Borges Keid, Dirk Hofreuter, Sascha Al Dahouk
Tags
canine brucellosis
Brucella canis
zoonotic disease
MALDI-TOF MS
whole-genome sequencing
outbreak analysis
epidemiology
Related Publications
Explore these studies to deepen your understanding of the subject.
