Peri-implant infection is a major threat to dental implant success. This study reports a novel N-halamine polymeric coating on titanium surfaces that provides long-lasting, renewable antibacterial efficacy with good stability and biocompatibility. The coating effectively combats key peri-implant infection bacteria both *in vitro* and *in vivo*, maintaining efficacy for 12-16 weeks. Its antibacterial properties can be renewed through simple rechlorination, offering a promising solution for preventing and treating peri-implant infections.
Publisher
Nature Communications
Published On
Jun 03, 2021
Authors
Shuyi Wu, Jianmeng Xu, Leiyan Zou, Shulu Luo, Run Yao, Bingna Zheng, Guobin Liang, Dingcai Wu, Yan Li
Tags
peri-implant infection
N-halamine
polymeric coating
antibacterial efficacy
biocompatibility
dental implants
rechiorination
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