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Isoform-level transcriptome-wide association uncovers genetic risk mechanisms for neuropsychiatric disorders in the human brain

Medicine and Health

Isoform-level transcriptome-wide association uncovers genetic risk mechanisms for neuropsychiatric disorders in the human brain

A. Bhattacharya, D. D. Vo, et al.

Discover the groundbreaking isoTWAS framework, which integrates genetics and isoform-level expression to revolutionize neuropsychiatric trait association studies. This research conducted by Arjun Bhattacharya, Daniel D. Vo, Connor Jops, Minsoo Kim, Cindy Wen, Jonatan L. Hervoso, Bogdan Pasaniuc, and Michael J. Gandal highlights the significance of isoform-level resolution in understanding complex traits.

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