This study presents four interpretable machine learning algorithms for predicting antimicrobial resistance in complicated urinary tract infections (UTIs). Using electronic health record data, the algorithms demonstrate high predictability of antibiotic resistance across four antibiotics. The methods' generalizability is shown on a separate uncomplicated UTI cohort. The approach aims to reduce ineffective treatments, facilitate rapid interventions, and enable personalized treatment suggestions, while also providing model interpretability.
Publisher
npj Antimicrobials & Resistance
Published On
Nov 02, 2023
Authors
Jenny Yang, David W. Eyre, Lei Lu, David A. Clifton
Tags
antimicrobial resistance
machine learning
urinary tract infections
predictive algorithms
personalized treatment
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