Current biomedical materials often mismatch tissue mechanics and leach chemicals, posing health risks. This study introduces injectable, non-leaching elastomers with tissue-like properties, enabling minimally invasive implantation. The elastomers' curing time is tunable, supporting various applications. In vitro studies show cell proliferation, while in vivo tests demonstrate implant integrity, mild inflammation, and minimal fibrosis.
Publisher
Nature Communications
Published On
Jun 25, 2021
Authors
Erfan Dashtimoghadam, Farahnaz Fahimipour, Andrew N. Keith, Foad Vashahi, Pavel Popryadukhin, Mohammad Vatankhah-Varnosfaderani, Sergei S. Sheiko
Tags
biomedical materials
injectable elastomers
tissue mechanics
cell proliferation
in vivo tests
implant integrity
non-leaching
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